It’s much more intuitive and organic to create the beats in real time with a MIDI input (especially one that is velocity sensitive), and you usually end up with something that is way different and more distinctive than if you had plotted it out with a mouse, and in much less time. What you start with is an uninspired sequence that you have to manipulate far too much to sound like anything that is really distinctive and interesting. There are several ways to make beats, but about the most uninspiring ways is plotting out beats with a mouse on a step sequencer or piano roll.